Immunological reaction against erythropoietin causing red-cell aplasia
نویسندگان
چکیده
منابع مشابه
Pure Red Cell Aplasia Induced by Antibodies against Human Recombinant Erythropoietin
Human recombinant erythropoietin (epoetin) is a very effective and safe biopharmaceutical. However, in 1998 the incidence of pure red cell aplasia (PRCA) induced by antierythropoietin (anti-EPO) antibodies in patients treated with epoetin started to increase. PRCA is a rare condition of non-regenerative anemia which can be associated with a variety of diseases and is in some cases of immunologi...
متن کاملPure red cell aplasia due to antibody against erythropoietin in hemodialysis patients
BACKGROUND Anemia is a common complication of chronic renal failure due to reduce erythropoietin production by kidneys. Anemia treated with recombinant human erythropoietin (rHu-EPO). Pure red cell aplasia (PRCA) due to antibody productionagainst rHu-EPO is a rare but major complication of this drug. OBJECTIVES The aim of this study was to determine the prevalence of PRCA due to antibodies in...
متن کاملRed cell aplasia in children
Red cell aplasia in children is a condition characterised by failure of erythropoiesis, with normal production of white blood cells and platelets. The disorder is either acquired or constitutional (congenital or inherited). The constitutional disorder is usually permanent, while the acquired variety is often transient, and thereby differs from adult pure red cell aplasia. As the treatment and p...
متن کاملRed cell aplasia in children
Red cell aplasia in children is a condition characterised by failure of erythropoiesis, with normal production of white blood cells and platelets. The disorder is either acquired or constitutional (congenital or inherited). The constitutional disorder is usually permanent, while the acquired variety is often transient, and thereby differs from adult pure red cell aplasia. As the treatment and p...
متن کاملAcquired pure red cell aplasia.
Correspondence MEDICALTJOSRNAL 559 Acquired Pure Red Cell Aplasia SIR,-May we make the following observation about your article on acquired pure red cell aplasia and its treatment with steroids (6 April, p. 3) ? A pure red cell aplasia that responded to riboflavine or prednisone has been described in African adults and in children with marasmus and kwashiorkor.' In marasmus and kwashiorkor an e...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2002
ISSN: 1460-2385
DOI: 10.1093/ndt/17.5.943